Graduate School of Information Sciences, Tohoku University key visual

OBAYASHI LAB.

What's New

  • 2025.4.1 Professor Takeshi Obayashi has been appointed Vice President of the Japanese Society for Bioinformatics.
  • 2025.4.1 We are pleased to welcome a new member to our lab.

Bioinformatics for Earth

Today's vigorous human activities threaten the sustainability of the natural world, and there is an urgent need to understand the current situation and take appropriate measures accurately. Meanwhile, we can "see" the world more accurately than ever, thanks to vast amounts of data.

Our laboratory extracts knowledge from the vast amount of data in the life sciences. We use a multilevel approach, from the gene level to the population level, to elucidate living systems as individuals or populations. We also work on the appropriate management and utilization of natural resources.

data collection
Gene Image
Image under study
demo

Basic Research

Systems Genomics

Complex systems are composed of combinations of simpler elements. In living systems, tens of thousands of genes are elaborately combined to form cellular systems, and different types of cells are combined to form tissues, organs, and individual systems. The genome, which consists of the four letters of ACGT, is the encoded multilevel system that makes up a given species. Correctly deciphering it reveals the characteristics and weaknesses of the system. In particular, gene expression data (transcriptome data) is a fundamental resource that reflects the relationship between genes and cells. We extract information from this data using the approach of gene expression and co-expression and make it available as a database.

Basic Research

Marine Ecosystem Dynamics

The oceans, which cover about 70% of the Earth's surface, form a complex ecosystem inhabited by diverse life forms, from microorganisms to whales. We humans receive immense direct and indirect benefits from these seas, making the understanding and management of the marine environment an extremely important issue. Inaugurated in 2024 as a world-class research initiative, the Advanced Institute for Marine Ecosystem Change (WPI-AIMEC) is on a mission to explore the response and adaptation mechanisms of marine ecosystems to changes in the Earth's system, through an international and interdisciplinary research team. In particular, the Obayashi Unit in WPI-AIMEC, in collaboration with the Onagawa Field Center, aims to comprehensively elucidate the biological dynamics of Onagawa Bay through the analysis of physicochemical data and plankton genome analysis based on long-read sequencing. Furthermore, using Onagawa Bay as a model case, the unit strives to elucidate the marine dynamics of the Sanriku coast, ultimately contributing to environmental conservation on a global scale.

Onagawa Bay Photo

Applied Research

We aim to solve social issues by utilizing the technologies and resources developed in the basic theme.

Bioenergy production

Photosynthesis is a reaction that uses light energy to fix carbon dioxide and attracts significant attention as a form of renewable energy. This research aims to produce bioenergy from microalgae by enhancing their lipid metabolism system and improving their culture efficiency.

Resource management

As an island nation, Japan has long utilized many fishery resources. In recent years, global demand for fishery resources has increased, and the sustainability of the fishing industry has become more critical than ever. Fish stock enhancement, famous for the release of salmon, enhances fishery resources by artificially hatching, growing, and releasing juveniles of fish. It is practiced in 40 countries around the world, including Japan. On the other hand, it is not well understood whether the released fish are only caught or contribute to further reproduction in nature. In this study, we estimate the kinship relationship between released and natural individuals to understand the fisheries resource dynamics under the fish stock enhancement program.

Evolution triggered by human activity

Human activities have a significant impact on ecosystems at various levels. Recent advances in genome analysis technology have revealed the phenomenon of "self-domestication," in which organisms with traits more likely to coexist with human activities are enhanced in each region. On the other hand, humans have long engaged in trade to link regional goods and information, contributing to habitat expansion and disturbance. The history of trade in each region is key to dealing with biological evolution at the global level. However, because many societies are illiterate, many areas remain black boxes. This study takes the approach of inferring the geographic origin of a word from its inter-language similarity and attempts to elucidate how natural resources in each region have been transmitted and utilized.

Members

Professor Takeshi Obayashi TAKESHI
OBAYASHI
  • Professor

    Takeshi OBAYASHI

  • Assistant Professor

    Katsuya UCHIDA

  • Associate Professor

    Tomoko HAMABATA

  • Specially Appointed Research Fellow

    Batdulam BATTULGA

  • Technical Assistant

    Akane KITAMURA

  • Secretary

    Aiko NAGATA

  • M2

    Shoma HEMMI

  • M1

    Daffa APRILIO

  • M1

    Jaronchai DILOKKALAYAKUL

  • M1

    Namuunbayar GANCHIMEG

  • M1

    Naoki SUGIMURA

  • B4

    Hayate KATO

Advanced Institute for Marine Ecosystem Change (WPI-AIMEC) Coastal Ecosystem Services Research Unit

  • Takeshi OBAYASHI

    Unit Leader (Graduate School of Information Sciences, Professor)

  • Minoru IKEDA

    AIMEC Researcher (Onagawa Field Center, Graduate School of Agricultural Science, Professor)

  • Toyonobu FUJII

    AIMEC Researcher (Onagawa Field Center, Graduate School of Agricultural Science , Assoc. Professor)

  • Tomoko HAMABATA

    AIMEC Researcher

  • Akane KITAMURA

    AIMEC Tech. Asst.

  • Batdulam BATTULGA

    AIMEC Specially Appointed Research Fellow

  • Diego DEVILLE CACERES

    AIMEC Specially Appointed Research Fellow

Professor Takeshi Obayashi TAKESHI
OBAYASHI

Recruitment

The Obayashi Laboratory is currently looking for members to join us in advancing data science!
If you're interested, please feel free to contact Obayashi.

Access

Graduate School of Information Sciences, Tohoku University
6-3-09, Aramaki-Aza-Aoba, Aoba-ku, Sendai 980-8579, Japan

Our laboratory is on the 2nd floor of the Graduate School of Information Science building.

Exterior view of Tohoku University